Description:

Multiplate®ASAReagent isareagentkitcontainingaspirin(acetylsalicylicacid,ASA) at30mg/mLtobeusedasaqualitycontrolmaterialinplateletaggregationstudieswiththeMultiplate® analyzer.

Acetylsalicylicacidproducesanantiplateleteffectbyinhibitingtheproductionofthromboxane,whichundernormalcircumstancespromotesplateletbindingtoeachotherandtheinjurysiteofthedamagedwallsofbloodvessels.

Pleasenotethecatalog#forMultiplateASAControlKithaschangedto08115796001.Youmayhavepreviouslyorderedthisproductundercatalog#sMP0270or06675921190.

KitComposition:

Reagents,StorageandStABIlity

• 08115796001: Multiplate®ASAReagentreagent, Kit,acetylsalicylicacid,3x1.0mL,lyophilized(30mg/mL),withoutmicrotest tubesforaliquotation. UnopenedvialsofASAControlreagentmustbestoredat 2-8°C.Thereagentisstableuntiltheexpirydateprinted ontheviallabelwhenstoredundertheseconditions.If reconstitutedreagentisnotaliquotedintomicrotest tubes,theoriginalvialshouldbestoredinanupright position. Stablefor7daysafterreconstitutionwhenstoredat 2-8°C,4weeksat<-20°C,or24hoursatroomtemperatureafterone timethawing.

Alsoavailable

• 06675743190: Multiplate®ASAReagentAliquotVials, Bag,100microtubescolorcoded(0range)foraliquotation.

Nolonger available

• MP0170: Multiplate®ASAControlreagent, Kit,acetylsalicylicacid,1x1.0mL,lyophilized(30mg/mL),with5microtesttubes foraliquotation.
• MP0510: Multiplate®ASAControlreagent, Kit,acetylsalicylicacid,1x1.0mL,lyophilized(30mg/mL),withoutmicrotest tubesforaliquotation.

MeasurementPrinciple:

AdditionofASAControltobloodsamplesleadstoreducedaggregationintheASPItestandtheCOLtest. Uponadditiontothebloodsample,theplateletcyclooxygenasepathwayisblockedandthecyclooxygenase-dependentMultiplatetests,ASPItestandCOLtestareinhibited.Thisallowstheassessmentofanabnormalresponseinthesetests.

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