Tocris/淀粉样蛋白β-肽(1-42)(大鼠)/2425/500U/500微克

价格
¥6900.00
货号:2425/500U
浏览量:127
品牌:Tocris
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商品描述
Description:Predominantamyloidβ-proteinfragment
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Ratformofthepredominantamyloidβ-peptidefoundinplaquesassociatedwithAlzheimer'sdisease.Leadstoalargeshiftinthebax/bcl-2ratioinfavourofpro-apoptoticbax.Neurotoxic.

TechnicalData

M.Wt4417.99
FormulaC199H307N53O59S
SequenceDAEFGHDSGFEVRHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
StorageDesiccateat-20°C
CASNumber166090-74-0
PubChemID71581490
InChIKeyHAWSUONKNKRLRH-ANECVMDESA-N
Smiles[H]N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlin0.1%Ammonia

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight4417.99.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.23mL1.13mL2.26mL
5mM0.05mL0.23mL0.45mL
10mM0.02mL0.11mL0.23mL
50mM0mL0.02mL0.05mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet