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蚂蚁淘在线 / 品牌中心 / Tocris / Tocris/NVP BHG 712/4405/1/1 mg

Tocris/NVP BHG 712/4405/1/1 mg

价格
￥2100.00
货号：4405/1
浏览量：127
品牌：Tocris
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商品描述
Description:PotentEphB4kinaseinhibitor
ChemicalName:4-Methyl-3-[[1-methyl-6-(3-pyridinyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]amino]-N-[3-(trifluoromethyl)phenyl]benzamidetrifluoroacetate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveinhibitorofEphB4kinase;exhibitsselectivityforEphB4overmorethan40otherkinasesinvitro,includingFGFR3.InhibitsEphB4autophosphorylationintransientlytransfectedHEK293cells.AlsoinhibitsVEGF-inducedangiogenesisinvivo;thoughttoinhibitEphB4forwardsignaling.Orallyactive.

TechnicalData

M.Wt617.5
FormulaC26H20F3N7O.CF3CO2H
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber940310-85-0
PubChemID73332408
InChIKeyKCYJGZKWKFCVGC-UHFFFAOYSA-N
SmilesCN1N=CC2=C1N=C(C4=CC=CN=C4)N=C2NC3=CC(C(NC5=CC=CC(C(F)(F)F)=C5)=O)=CC=C3C.OC(C(F)(F)F)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO24.740

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight617.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.62mL8.1mL16.19mL
5mM0.32mL1.62mL3.24mL
10mM0.16mL0.81mL1.62mL
50mM0.03mL0.16mL0.32mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet