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蚂蚁淘在线 / 品牌中心 / Tocris / 托克里斯/甲磺酸曲伐沙星/3863/50/50毫克

托克里斯/甲磺酸曲伐沙星/3863/50/50毫克

价格
￥16500.00
货号：3863/50
浏览量：127
品牌：Tocris
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商品描述
Description:Antibiotic;inhibitsbacterialDNAsynthesis
AlternativeNames:CP99219
ChemicalName:7-[(1α,5α,6α)-6-Amino-3-azABIcyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylicacidmesylate
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Fluoroquinoloneantibiotic.InhibitsbacterialDNAtopoisomeraseIVandDNAgyraseandformsastablequinolone-DNAcomplexwiththeseenzymeswhichreversIBLyinhibitsDNAsynthesis.Displayspotentactivityagainstgram-positiveandgram-negativebacteria.IncreasestheproductionofmitochondrialNOinimmortalizedhepatocytes;alsoincreasesmitochondrialCa2+.InhibitsPanx-1(IC50~4μM).

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

CompoundLibraries

TrovafloxacinmesylateisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt512.46
FormulaC20H15F3N4O3.CH3SO3H
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber147059-75-4
PubChemID62960
InChIKeyDYNZICQDCVYXFW-GIPYJWDTSA-N
SmilesO=C2C1=CC(F)=C(N4C[C@@]([C@H]5N)([H])[C@@]5([H])C4)N=C1N(C3=C(F)C=C(F)C=C3)C=C2C(O)=O.CS(=O)(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO51.25100
water25.6250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight512.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.95mL9.76mL19.51mL
5mM0.39mL1.95mL3.9mL
10mM0.2mL0.98mL1.95mL
50mM0.04mL0.2mL0.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet