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蚂蚁淘在线 / 品牌中心 / Tocris / Tocris/AZM 475271/3963/10/10毫克

Tocris/AZM 475271/3963/10/10毫克

价格
￥4700.00
货号：3963/10
浏览量：127
品牌：Tocris
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商品描述
Description:Srctyrosinekinaseinhibitor
ChemicalName:N-(2-Chloro-5-methoxyphenyl)-6-methoxy
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Srctyrosinekinaseinhibitor.Reducestumorsize,vascularityandmetastasis,andincreasesapoptosisinhumanpancreaticcellsgrowninnudemice.Alsoexhibitsantiangiogenicactivityinvitroandinvivo.SensitizestumorcellstothecytotoxiceffectsofgemcitABIne(Cat.No.3259).

LicensingInformation

SoldwiththepermissionofAstraZenecaUKLtd.

CompoundLibraries

AZM475271isalsoofferedaspartoftheTocriscreenPlusandTocriscreenKinaseInhibitorToolboxI.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt442.94
FormulaC23H27ClN4O3
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber476159-98-5
PubChemID5330175
InChIKeyWPOXAFXHRJYEIC-UHFFFAOYSA-N
SmilesClC1=CC=C(OC)C=C1NC3=NC=NC2=CC(OCC4CCN(C)CC4)=C(OC)C=C23

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO44.29100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight442.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.26mL11.29mL22.58mL
5mM0.45mL2.26mL4.52mL
10mM0.23mL1.13mL2.26mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet