The EarlyTox™ Cardiotoxicity Kit provides a fast, simple, and reliable fluorescence-based method for identifying cardiotoxic compounds in a biorelevant assay using stem-cell derived cardiomyocytes. Leveraging our proprietary masking technology with our novel calcium sensitive indicator, researchers can:

•     Eliminate cardiotoxic compounds and identify potential drug candidates
•     Measure 384 samples in minutes rather than hours
•     Minimize non-specific effect of dye on beat characteristics
•     Reduce well-to-well variation and improve data quality
•     Largest signal dynamic range available
•     Benchmark against three reference compounds: isoproterenol, sotalol and propranolol

 

 

Available Configurations:

Configuration	Description	Part Number
Explorer Kit	(2) Vials of Component A* (1) Bottle of dilution buffer (Component B) (1) Vial each of three reference compounds: isoproterenol, sotalol, and propranolol *Each reagent vial (Component A) is sufficient for 1 plate (96- or 384-wells). Each kit is sufficient for 2 plates.	(R8210)
Bulk Kit	(2) Vials of Component A** (1) Bottle of dilution buffer (Component B) (1) Vial each of three reference compounds: isoproterenol, sotalol, and propranolol **Each reagent vial (Component A) is sufficient for 5 plates (96-, 384- or 1536-wells). Each kit is sufficient for 10 plates.	(R8211)

 

 

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