Citric acid hydrate; citrate

C-2763

5949-29-1

2-hydroxypropane-1,2,3-tricarboxylic acid;hydrate

C₆H₈O₇ • H₂O

210.14 Da

White crystalline powder

≥99%

165 g in 100 mL water at 20ºC

135 - 152 °C

Room temperature

Not Applicable

Citric Acid Monohydrate is an acidic compound from citrus fruits; as a starting point in the Krebs cycle, citrate is a key intermediate in metabolism. Citric acid is one of a series of compounds responsible for the physiological oxidation of fats, carbohydrates, and proteins to carbon dioxide and water. It has been used to prepare citrate buffer for antigen retrieval of tissue samples. The citrate solution is designed to break protein cross-links, thus unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, and resulting in enhanced staining intensity of antibodies. Citrate has anticoagulant activity; as a calcium chelator, it forms complexes that disrupt the tendency of blood to clot. May be used to adjust pH and as a sequestering agent for the removal of trace metals.

Irritant

Ensure adequate ventilation, especially in confined areas. Keep away from heat, sparks, flame and other sources of ignition (i.e., pilot lights, electric motors and static electricity). Take precautionary measures against static discharges. Use spark-proof tools andexplosion-proof equipment. All equipment used when handling the product must be grounded. Use with local exhaust ventilation. Use personal protective equipment as required. Do not breathe dust/fume/gas/mist/vapors/spray.

C-2763 Citric Acid Monohydrate ACS, SDS, diamond format.pdf

C-2763, K1156A.pdf