Catalog Number:  26219

Gene Symbol:  PIK3CA, CLOVE, CWS5, MCAP, MCM, MCMTC, PI3K, p110-alpha

Description:  Anti-PIK3CA (G1049S) Mouse Monoclonal Antibody

Background:  Phosphatidyl 3-kinases (PI3K) are a family of lipid kinases involved in many cellular processes, including cell growth, proliferation, differentiation, motility, and survival. It is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. Mutants of PIK3CA has been found in the pathogenesis of several cancers, including colon cancer, gliomas, gastric cancer, breast cancer, endometrial cancer, and lung cancer.

Immunogen:  A synthetic peptide from the internal region of PIK3CA which includes the mutation of G1049S, human origin.

Applications:  ELISA, WB

Recommended Dilutions:   ELISA:1:1000-1:5000 WB: 1:500-1:2000

Concentration:   1 mg/ml

Host:  Mouse

Format:   Liquid

Clonality:   Monoclonal

Isotype:

Purity:   Purified from ascites

Storage buffer:

Preservative:  no

Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol

Species Reactivity:  Recognizes G1049S mutant, but not wild-type PIK3CA of vertebrates.

Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles

Download Datasheet:

Western blot:

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