Description:

The human interferon-beta 2 gene(IFNB2) product is identical to that for the B-cell stimulation factor-2(BSF-2), the hybridoma growth factor(HGF)(\"interleukin-6\"), and the hepatocyte stimulating factor(HSF). Proteins derived from this gene mediate the plasma protein response to tissue injury(acute-phase response) and regulate the growth and differentiation of both B and T cells. Interleukin-6(IL6) has come to be regarded as a potential osteoporotic factor because it has stimulatory effects on cells of the osteoclast lineage, and, thus, may play a role in the pathogenesis of bone loss associated with estrogen deficiency. IL-6 has many roles essential to the regulation of the immune response, hematopoiesis, and bone resorption. It is involved not only in the hepatic acute phase response but also in adipose tissue metabolism, lipoprotein lipase activity, and hepatic triglyceride secretion. Overproduction of IL-6, a proinflammatory cytokine, is associated with a spectrum of age-related conditions including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes, certain cancers, periodontal disease, frailty, and functional decline. BSF-2 is a novel interleukin consisting of 184 amino acids. The standard product used in this kit is recombinant human IL-6, consisting of 184 amino acids with the molecular mass of 20.3kDa.

Additional Information:

Name Related Product Names Short Description Immunogen Standard Range Sample Type Specimen/Volumes Swiss Prot Number Concentration Applications GI Number Stability Reactivity Kit Size Storage Intended Use

Human IL-6 ELISA Kit

B cell differentiation factor|B cell stimulatory factor 2|B-cell stimulatory factor 2|BSF 2|BSF-2|BSF2|CDF|CTL differentiation factor|Cytotoxic T cell differentiation factor|Hepatocyte stimulating fact|HGF|HPGF|HSF|Hybridoma growth factor|

Sandwich ELISA kit of Quantitative Detection for Human IL-6

E.coli, P29-M212

4.69pg/ml-300pg/ml. Test has a sensitivity of

This kit is used for quantitative detection of human IL-6 in cell culture supernates, serum and plasma(heparin, EDTA, citrate).

Refer to Manual

B4DVM1

Lot Specific

ELISA

3569

Four months at 4C and eight months at -20C.

Reactive to Human. There is no detectable cross-reactivity with other relevant proteins.

1x96 well plate

Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)

Research Use Only

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