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Vineomycinone B2

Chemical

C25H26O10

486.5

30270-05-4

Isolated from Streptomyces parvulus.

≥97% (HPLC, NMR)

Yellow to orange solid.

Soluble in DMSO. Sparingly soluble in methanol or acetone.

Determined by 1H-NMR and MS.

Manufactured by BioViotica.

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AMBIENT

+4°C

-20°C

Protect from light.

Stable for at least 1 year after receipt when stored at -20°C.Store solutions at -20°C in the dark.

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• C-glycosidic angucyclinone derivative.
• Antibiotic.
• Antitumor agent.
• Antibacterial agent.
• Isomer of fridamycin B (Prod. No. BVT-0470).

Product References

The structure of vineomycin B2: N. Imamura, et al.; J. Antibiot. 34, 1517 (1981)

Fridamycine, Anthracyclin-analoge Antibiotica: P. Knicke; Ph. D. Thesis Univ. Goettingen (1984)

Angucycline group antibiotics: J. Rohr & R. Thiericke; Nat. Prod. Rep. 9, 103 (1992)

Synthetic anthracyclines from anthraquinones: R. Cambie, et al.; Austr. J. Chem. 45, 483 (1992)

C-Aryl glycosides via tandem intramolecular benzyne-furan cycloadditions. Total synthesis of vineomycine B2 methyl ester: C.-L. Chen, et al.; JACS 128, 13696 (2006)

Convergent de novo synthesis of vineomycinione B2 methyl ester: Q. Chen, et al.; Chem. Comm. 49, 6806 (2013)

Total Synthesis of vineomycin B2: S. Kusumi, et al.; JACS 135, 15909 (2013)

Angucycline antibiotics and its derivatives from marine-derived actinomycete streptomyces sp. A6H: Z. Hu, et al.; Nat. Prod. Res. (Epub ahead of print) (2016)

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