- morphine receptor activity Antibodies | Invitrogen
- Synaptic Systems 品牌介绍及代理商/经销商名单 ...
- 财务管理如何为汽车终端销售企业提供支撑
- neuroscientific_双语例句
- 芭芭多芦荟产品价格在哪里查询有谁知道?
- Neuromics 品牌介绍及代理商/经销商名单品牌专区 ...
- AntiFas (CD95) mAb
- 网易视频母亲承诺房屋给女儿,如今母亲去世,不料其余兄妹却要来分房
- Neuromics 博奥派克
- SHPRH Antibody (RA19057100UL)
- 基材弹性模量对兔纤维环源干细胞和骨髓间充质干细胞分化调控的...
- Neuromics品牌馆,Neuromics INC现货,Neuromics代理,Neuromics ...
Type:Protein
SpeciesReactivity:H
B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;AllSMAD2ispartoftheSMADfamilyofproteinsthatmediatesignaltransductionbytheTGF-beta/activin/BMP-2/4cytokinesuperfamilyfromreceptorSer/Thrproteinkinasesatthecellsurfacetothenucleus.PhosphorylatedSMAD2isthenabletoformacomplexwithSMAD4orSARA.Thesecomplexesaccumulateinthecellnucleus,wheretheyaredirectlyparticipatingintheregulationofgeneexpression.
SMAD2mediatesthesignaloftheTGF-beta,andthereforeregulatesmultiplecellularprocesses,suchascellproliferation,apoptosis,anddifferentiation.SMAD2isrecruitedtotheTGF-betareceptorsthroughitsinteractionwiththeSMADanchorforreceptoractivation(SARA)protein. TGF-beta1actsonadjacentstromalcellstoturnonSMAD2signallingthatcouldleadtostromaldecidualization.SMAD2isthedownstreamsignaltransducersofTGF-beta-1inhumandentalpulpcells.
