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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
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info@ebiomall.com
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商品描述
Overview:
PI3K(p55gamma)alsoknownasPI3Kregulatorysubunit3(PIK3R3)wasfirstidentifiedby2-hybridsystemasaproteinthatbindtotheintracellulardomainofIGF1R.PIK3R3contains2Srchomology-2(SH2)domains,aninter-SH2/p110-bindingsiteandaproline-richmotif.PIK3R3transcriptisdetectedinallfetalandadulttissuesexceptperipheralbloodleukocytes.Expressionislowinadultliverandmostabundantinadulttestis.PIK3R3canbindIGF1R,INSR,andINSRsubstrate-1invitroandthebindingrequiresreceptoractivation(1).
GeneAliases:
PIK3R3,p55,p55-GAMMA,FLJ41892,DKFZp686P05226
GenbankNumber:
BC021622
References:
1.Dey,BR.etal:Cloningofhumanp55-gamma,aregulatorysubunitofphosphatidylinositol3-kinase,byayeasttwo-hybridlibraryscreenwiththeinsulin-likegrowthfactor-Ireceptor.Gene209:175-183,1998.
