- Peptide Substrates
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- Secondary Antibodies
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- E2
- Assay Buffer and Co-factors
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- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
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- Carbohydrate Substrates
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- E3
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- SignalChem|生产厂家|价格信息
- signalchem
- IL4 Gene GeneCards | IL4 Protein | IL4 Antibody
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Overview:
STK19isamemberoftheserine/threoninekinasefamilythatshowsamanganese-dependentproteinkinaseactivityandphosphorylatesα-caseinatser/thrresiduesandhistoneatserresidues.STK19containsapositivelychargedputativenuclearlocalizationsignal,multiplepotentialphosphorylationsites,2amidationsites,9potentialN-myristoylationsites,andnoN-glycosylationsites.STK19hasbeenshowntolocalizepredominantlyinthenucleus(1).ThephosphorylationofSTK19isthoughttobeinvolvedintranscriptionalregulation.STK19localizestothemajorhistocompatibilitycomplex(MHC)classIIIregiononchromosome6(2).
GeneAliases:
D6S60;D6S60E;G11;HLA-RP1;RP1
GenbankNumber:
NM_004197
References:
1.Gomez-Escobar,N.et.al:TheG11genelocatedinthemajorhistocompatibilitycomplexencodesanovelnuclearserine/threonineproteinkinase.J.Biol.Chem.273:30954-30960,1998.2.Shen,L.et.al:StructureandgeneticsofthepartiallyduplicatedgeneRPlocatedimmediatelyupstreamofthecomplementC4AandtheC4BgenesintheHLAclassIIIregion:molecularcloning,exon-intronstructure,compositeretroposon,andbreakpointgeneduplication.J.Biol.Chem.269:8466-8476,1994.
