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蚂蚁淘在线 / 品牌中心 / Tocris / Tocris/Verteporfin/5305/10/10 mg

Tocris/Verteporfin/5305/10/10 mg

价格
￥3380.00
货号：5305/10
浏览量：127
品牌：Tocris
服务
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商品描述
Description:YAPinhibitor;disruptsYAP-TEADinteractions
AlternativeNames:Visudyne
ChemicalName:(4R,4aS)-18-Ethenyl-4,4a-dihydro-3,4-bis(methoxycarbonyl)-4a,8,14,19-tetramethyl-24H,26H-benzo[b]porphine-9,13-dipropanoicacidmonomethylester
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

YAPinhibitor;disruptsYAP-TEADinteractions.EnhancestrypsincleavageofYAP(EC50=100nM).Inhibitsgrowthandproliferationofretinoblastomacells.Alsosuppressescancerstemcellpropertiesinvitro.SuppressesYAP-inducedliverovergrowthinmice.

TechnicalData

M.Wt718.79
FormulaC41H42N4O8
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber129497-78-5
PubChemID5362420
InChIKeyYTZALCGQUPRCGW-ZSFNYQMMSA-N
SmilesCC(C(/C=C4N/C([C@@]5(C)C4=CC=C(C(OC)=O)[C@H]5[C@](OC)=O)=CC6=NC(C(CCC(OC)=O)=C6C)=C3)=N2)=C(C=C)/C2=C/C1=C(C)C(CCC(O)=O)=C/3N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO14.3820

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight718.79.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.39mL6.96mL13.91mL
5mM0.28mL1.39mL2.78mL
10mM0.14mL0.7mL1.39mL
50mM0.03mL0.14mL0.28mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet